I’ve finally updated NWSGI to use IronPython 2.7: NWSGI 2.1. The only other change is that NWSGI.dll will be added to the GAC by default by the installer.
NWSGI 3 Update
The big feature of NWSGI 3 is decoupling it from IIS and ASP.NET, which involved creating an abstraction layer for web servers (which is funny, because that’s what WSGI is). Shortly after I started that, the OWIN project started, which has essentially the same goal. Since I hate duplicating effort, NWSGI 3 is on hold until OWIN stabilizes, which hopefully shouldn’t be too much longer.